ZIBIN ZHAO

A short story我的故事

PhD candidate in Bioengineering at the Hong Kong University of Science and Technology (Hsing Lab), HKPFS + Redbird awardee. BSc Biomedical Engineering, University of Melbourne (First Class Honours). I build deep-learning methods at the interface of molecular biology and AI — one-pot CRISPR diagnostics, structure-aware aptamer selection, and molecular-dynamics tooling.

香港科技大学生物工程博士候选人（Hsing 实验室），香港博士研究生奖学金（HKPFS）+ Redbird 奖得主；本科毕业于墨尔本大学生物医学工程（一等荣誉）。我在分子生物学与人工智能的交叉处构建深度学习方法 —— 一锅式 CRISPR 诊断、结构感知的适体筛选，以及分子动力学工具。

Selected work代表性成果

• 2026

  DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage★

  Nature Biotechnology

  X Wu, WH Lam, Z Zhao, Y Cao, H Lin, X Feng, Y Zhai, IM Hsing

  DOI
• 2026

  Thermodynamically programmed one-pot CRISPR platform for point-of-care SNP genotyping

  IM Hsing, X Wu, Y Li, Y Cao, Z Zhao, H Lu, S Liang
• 2025

  Benchtop to at-home test: amplicon-depleted CRISPR-regulated loop-mediated amplification at skin-temperature for viral load monitoring

  Biosensors and Bioelectronics, 267

  Y Cao, H Lin, X Lu, X Wu, Y Zhu, Z Zhao, Y Li, et al.

  DOI
• 2025

  Structure-enhanced deep learning accelerates aptamer selection for small molecule families like steroids★

  Briefings in Bioinformatics, 26(6)

  Z Zhao, H Lin, HY Lau, H Chen, IM Hsing

  DOICODE
• 2025

  DNA-guided CRISPR/Cas effector for programmable RNA-recognition and cleavage

  IM Hsing, X Wu, Z Zhao, Y Cao, H Lin, X Feng
• 2025

  DNA hydrogel-interfaced organic electrochemical transistor for the investigation of binding-induced conformational change of small molecule aptamers

  ACS Applied Materials & Interfaces, 17(37)

  H Lin, Z Zhao, X Feng, SY Yeung, IM Hsing

  DOI
• 2023

  Skin-adherent elastomer-hydrogel patch for continuous 12-lead cardiac ambulatory monitoring during physical activities

  Advanced Materials Technologies, 8(18)

  Y Li, Z Zhao, A Veronica, S Yu Yeung, IM Hsing

  DOI
• 2023

  Transforming ECG diagnosis: an in-depth review of transformer-based deep-learning models in cardiovascular disease detection★

  arXiv:2306.01249

  Z Zhao

  PDF
• 2023

  Integrating magnetic-bead-based sample extraction and molecular barcoding for the one-step pooled RT-qPCR assay of viral pathogens without retesting

  Analytical Chemistry, 95(14)

  X Zhuang, Z Zhao, X Feng, GCY Lui, D Chan, SS Lee, IM Hsing

  DOI

Things I've built我做过的东西

Built for the joy of it 🛠️为热爱而造 🛠️

Things I've vibe-coded — shipped fast with AI pair-programming. Side projects where curiosity leads and the build follows.

我随性编写的小项目 —— 借助 AI 结对编程快速落地。好奇心在前，代码随后。

Singularity 奇点

A live universe of 400,000 GPU particles morphing between a galaxy, a black hole, DNA and any word you type — bend it with your finger. Pure math, no textures, 60fps in the browser.40 万 GPU 粒子组成的实时宇宙 —— 在星系、黑洞、DNA 与任意文字之间变形，指尖即可弯曲时空。纯数学渲染，无贴图，浏览器内 60fps。

Three.jsGLSLWebGLClaude Code

View →查看 →

Yaos 药师法门 · 养生

An installable PWA that auto-detects your current 时辰 & 节气 to surface personalized Medicine-Buddha health-cultivation advice, with readings & a calendar.可安装的 PWA，自动识别当前时辰与节气，提供个性化的药师法门养生建议，并附经文阅读与日历。

PWAHTML/JSWellnessClaude Code

View →查看 →

screenshot — coming soon截图 —— 即将上线

Zen 禅德 · Zende

A WeChat Mini Program for meditation & mindfulness — guided sessions, journaling, streaks, a virtual pet & Buddhist calendar. Apple-style glassmorphism.冥想与正念的微信小程序 —— 引导练习、修行日记、连续打卡、虚拟宠物与佛历，Apple 风格玻璃拟态设计。

uni-app/VueWeChatCloud DBClaude Code

Coming soon即将上线

+

Open slot — more projects to come虚位以待，更多项目即将到来